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| Kat. Nr. | Arten | Produktbeschreibung | Struktur | Reinheit | Merkmal |
|---|---|---|---|---|---|
| COS-H52H3 | Human | Human Complement C1s Protein, His Tag |  |
|
| Name | Research Code | Research Phase | Company | First Brand Name | First Approved Country | First Indication | First Approved Company | First Approved Date | Indications | Clinical Trials |
|---|---|---|---|---|---|---|---|---|---|---|
| Conestat alfa | rhC1-INH | Approved | Pharming Group Nv | Rhucin, Esterasine, Ruconest | EU | Angioedemas, Hereditary | Pharming Group Nv | 2010-10-28 | Rejection of renal transplantation; Myocardial Infarction; Renal Insufficiency; Rejection of organ transplantation; Genetic Diseases, Inborn; Coronavirus Infections; Non-ST Elevated Myocardial Infarction; Angioedema; Angioedemas, Hereditary | Details |
| Sutimlimab | BIVV-009; TNT-009 | Approved | True North Therapeutics | ENJAYMO | United States | Anemia, Hemolytic, Autoimmune | Bioverativ Therapeutics Inc | 2022-02-04 | Hemolysis; Purpura, Thrombocytopenic, Idiopathic; Anemia, Hemolytic, Autoimmune; Pemphigoid, Bullous; Kidney Failure, Chronic | Details |
| Complement C1 inhibitor protein (Shire ViroPharma) | C1 INH-nf; C1-INH; SHP-616 | Approved | Sanquin Plasma Products Bv | Cinryze, Cetor | United States | Angioedemas, Hereditary | null | 2008-10-10 | Brain Injuries, Traumatic; Rejection of organ transplantation; Angioedemas, Hereditary | Details |
| C1 esterase inhibitor (Human, CSL Behring) | BI-3.012; CSL-830; CSL-842; CE-1145 | Approved | Csl Behring Llc | Berinert, Haegarda, Berinert 2000 | Japan | Angioedemas, Hereditary | Csl Behring Llc | 1990-06-29 | Hereditary Angioedema Types I and II; Angioedemas, Hereditary | Details |
| Conestat alfa | rhC1-INH | Approved | Pharming Group Nv | Rhucin, Esterasine, Ruconest | EU | Angioedemas, Hereditary | Pharming Group Nv | 2010-10-28 | Rejection of renal transplantation; Myocardial Infarction; Renal Insufficiency; Rejection of organ transplantation; Genetic Diseases, Inborn; Coronavirus Infections; Non-ST Elevated Myocardial Infarction; Angioedema; Angioedemas, Hereditary | Details |
| Sutimlimab | BIVV-009; TNT-009 | Approved | True North Therapeutics | ENJAYMO | United States | Anemia, Hemolytic, Autoimmune | Bioverativ Therapeutics Inc | 2022-02-04 | Hemolysis; Purpura, Thrombocytopenic, Idiopathic; Anemia, Hemolytic, Autoimmune; Pemphigoid, Bullous; Kidney Failure, Chronic | Details |
| Complement C1 inhibitor protein (Shire ViroPharma) | C1 INH-nf; C1-INH; SHP-616 | Approved | Sanquin Plasma Products Bv | Cinryze, Cetor | United States | Angioedemas, Hereditary | null | 2008-10-10 | Brain Injuries, Traumatic; Rejection of organ transplantation; Angioedemas, Hereditary | Details |
| C1 esterase inhibitor (Human, CSL Behring) | BI-3.012; CSL-830; CSL-842; CE-1145 | Approved | Csl Behring Llc | Berinert, Haegarda, Berinert 2000 | Japan | Angioedemas, Hereditary | Csl Behring Llc | 1990-06-29 | Hereditary Angioedema Types I and II; Angioedemas, Hereditary | Details |
| Name | Research Code | Research Phase | Company | Indications | Clinical Trials |
|---|---|---|---|---|---|
| Riliprubart | SAR-445088; TNT-020; BIVV-020 | Phase 3 Clinical | True North Therapeutics | Purpura, Thrombocytopenic, Idiopathic; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Polyneuropathies; Rejection of organ transplantation; Anemia, Hemolytic | Details |
| C1 esterase inhibitor (Boya Bio-Pharmaceutical) | Phase 3 Clinical | Boya Bio-Pharmaceutical Group Co Ltd | Angioedemas, Hereditary | Details | |
| Complement-C1 inhibitor protein (Octapharma) | Phase 2 Clinical | Octapharma | Angioedemas, Hereditary | Details | |
| DNTH-103 | DNTH-103; DNTH103 | Phase 2 Clinical | Dianthus Therapeutics Inc | Myasthenia Gravis; Autoimmune Diseases | Details |
| C1 esterase inhibitor (Chengdu Institute of Biological Products) | Phase 1 Clinical | Chengdu Institute Of Biological Products Co Ltd | Angioedemas, Hereditary | Details | |
| Riliprubart | SAR-445088; TNT-020; BIVV-020 | Phase 3 Clinical | True North Therapeutics | Purpura, Thrombocytopenic, Idiopathic; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Polyneuropathies; Rejection of organ transplantation; Anemia, Hemolytic | Details |
| C1 esterase inhibitor (Boya Bio-Pharmaceutical) | Phase 3 Clinical | Boya Bio-Pharmaceutical Group Co Ltd | Angioedemas, Hereditary | Details | |
| Complement-C1 inhibitor protein (Octapharma) | Phase 2 Clinical | Octapharma | Angioedemas, Hereditary | Details | |
| DNTH-103 | DNTH-103; DNTH103 | Phase 2 Clinical | Dianthus Therapeutics Inc | Myasthenia Gravis; Autoimmune Diseases | Details |
| C1 esterase inhibitor (Chengdu Institute of Biological Products) | Phase 1 Clinical | Chengdu Institute Of Biological Products Co Ltd | Angioedemas, Hereditary | Details |
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